A traditional Korean medicine shows powerful anti-wrinkle effects

As a person ages, the functions of skin cells decrease, which leads to the formation of wrinkles. To avoid this, researchers at the  University  of  Kyung Hee  suggest the use of the medicinal formula based on herbs Korean Seungma-Galgeun-Tang (SMGGT). Their study, published in  BMC Complementary and Alternative Medicine  , an anti - wrinkle potential determined based on the ability of SMGGT to reduce the production of metalloproteinase-1 of the matrix and increase procollagen type 1.

• SMGGT is a combination of the following herbs: Cimicifugae Rhizoma  ,  Puerariae Radix  ,  Paeoniae Radix  and  Glycyrrhizae Radix  .
• This traditional formulation was used to treat smallpox, measles and urticaria. Furthermore, SMGGT has also shown anti - inflammatory and antiallergic effects, and inhibitory effects on the cytopathic activity.
• The wrinkling is caused by reduced production of type I collagen, as well as an increase in production of matrix metalloproteinase. Exposure to UV can also increase the likelihood of wrinkling.
• For this study, the components found in SMGGT and their potential cytotoxicity were determined.
• All tests for wrinkleproofing potential and SMGGT cytotoxicity were performed in human dermal fibroblasts.

The results show that SMGGT can effectively inhibit the production of metalloproteinase-1 matrix. On the other hand, promotes procollagen type 1.  Together, these results show that SMGGT has potential use in products and wrinkle treatments.

Read the full text of the study  on the link  .